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Standard semaglutide titration: Weeks 1-4: 0.25 mg weekly Weeks 5-8: 0.5 mg weekly Weeks 9-12: 1.0 mg weekly Week 13+: 1.7 mg or 2.4 mg weekly (target dose) Hashimoto's-adjusted approach: Weeks 1-6: 0.25 mg weekly (extended to allow thyroid monitoring at week 6) Weeks 7-12: 0.5 mg weekly (TSH check before increasing) Weeks 13-16: 1.0 mg weekly Week 17+: Assess whether higher doses are needed The extended timeline allows for thyroid function checks at each step, ensuring levothyroxine doses are adjusted proactively rather than reactively

When combined, these effects compound: your heart works harder, blood vessel strain increases, and the risk of arrhythmias, chest pain, or blood pressure spikes rises substantially

It extends the GLOW blend with the addition of KPV for anti-inflammatory signaling research

The Reconstitution Calculator handles this automatically enter vial size, water amount, and target dose